Jonathan Pritchard

Our research group tackles the following questions. What is the nature and extent of genetic variation within and between populations? What are the biological and evolutionary processes that have produced the observed patterns of variation? How do genotypes contribute to phenotypes for complex traits (and how can we identify the relevant genetic variants)? The scope of our past and ongoing research includes work in four main areas:
  1. methods for gene mapping of complex traits;
  2. inference of population structure from genetic data
  3. history and structure of human populations; and
  4. genome variation and evolution.

Selected relevant publications: 

J. P. Noonan, G. Coop, S. Kudaravalli, D. Smith, J. Krause, J. Alessi, F. Chen, D. Platt, S. Paabo, J. K. Pritchard, and E.M. Rubin. Sequencing and analysis of Neanderthal genomic DNA. Science, 314:1113-1118, 2006.

D.F. Conrad, M. Jakobsson, G. Coop, X. Wen, J.D. Wall, N.A. Rosenberg, and J.K. Pritchard. A worldwide survey of haplotype variation and linkage disequilibrium in the human genome. Nature Genetics, 38:1251-1260, 2006.

D. Falush, M. Stephens, and J. K. Pritchard.  Inference of Population Structure Using Multilocus Genotype Data: Linked Loci and Correlated Allele Frequencies. Genetics, 164:1567-1587, 2003.

N. A. Rosenberg, J. K. Pritchard, J. L. Weber, H. M. Cann, K. K. Kidd, L. A. Zhivotovsky, and M. W. Feldman. Genetic structure of human populations. Science, 298:2381-5, 2002.

M. Beaumont, D. Gottelli, E. M. Barratt, A. C. Kitchener, M. J. Daniels, J. K. Pritchard, and M. W. Bruford. Genetic diversity and introgression in the Scottish wildcat. Molecular Ecology, 10:319-336, 2001.


J. K. Pritchard, M. Stephens, and P. Donnelly. Inference of Population Structure Using Multilocus Genotype Data. Genetics, 155:945-959, 2000.

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